Continuous Renal Replacement Therapy (CRPT) is a steady and continual process for the purification of blood. Continuous Renal Replacement Therapy (CRPT) performs all the tasks of the kidney. The kidneys of a person may not work properly due the disease, accident, or trauma. Continuous Renal Replacement Therapy (CRPT) is advised for patients with acute renal failure, circulatory problems, and liver problems.
Therefore, Continuous Renal Replacement Therapy (CRPT) carries out all the functions of kidneys such as, regulating the water level in the body, flushing out toxins and other wastes.
Benefits of Continuous Renal Replacement Therapy (CRPT)
Removes toxins from the blood and tissue
Continuous Renal Replacement Therapy (CRPT) removes the harmful uremic toxins from the blood along with the uremic toxins from the tissue. The penetrable hemofilter used in the CRPT therapy purifiers the blood and flush out the chemicals and waste products from the body in the form of urea.
Fewer side effects
Continuous Renal Replacement Therapy (CRPT) has fewer side effects than intermittent hemodialysis, as CRPT therapy removes toxins and other fluids slowly. CRPT therapy allows intravascular water refilling from the tissue, and reduces the risk of hypotension
Continuous Renal Replacement Therapy (CRPT) not only flushes out waste products from the kidneys, but also maintains essential fluid balance, acid balance, electrolyte balance and colloid osmotic pressure.
Types of CRPT
There are three main types of Continuous Renal Replacement Therapy (CRPT).
Membranes are the synthetic and biocompatible layer, which are used in CRPT for the maximal removal of water and waste from the body. Hemofilters and high-flux dialyzers are the membranes used in the process of Continuous Renal Replacement Therapy (CRPT). These membranes are highly efficient in absorbing proteins and purifying blood. Hemofilters and high-flux dialyzers have the capability to remove or reduce the size of cytokines. If, cytokines are not removed from the body, it can cause inflammation and may result in severe kidney complications
Continual Venovenous Hemofilteration
A Continual venovenous hemofilteration technique used in the CRPT is highly effective in the purification of blood and volume control. Physiological fluids are passed in the body for the removal of waste and for the purification of blood. These fluids also reduce the risk of instability and fulfill the loss of electrolytes
. Ultrafiltration and convection are used in this process, which ensures the appropriate removal of wastes and other products. This technique is also known as CVVH technique.
Continual Venovenous Hemodialysis
In Continual Venovenous Hemodialysis (CVVHD) technique, dialystate fluids are used for the removal of waste products. Dialystate fluids increase the chances of better results during dialysis. Continual Venovenous Hemodialysis removes the molecular waste at a faster rate. Dialystate fluids are can be obtained from the variety of sources but are not much cost, effective than other fluids used in the dialysis procedure
. However, these fluids have a high concentration of electrolytes, which keeps the blood cells healthy and resistant.
Complications of Continuous Renal Replacement Therapy (CRPT)
Some of the risks and complications associated with CRPT are: