TYPICAL USAGE:

Moxifloxacin is used to treat a variety of bacterial infections. This medication belongs to a class of drugs called quinolone antibiotics. It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for virus infections (such as common cold, flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.

SIDE EFFECTS:

Moxifloxacin may cause swelling or tearing of (rupture) a tendon, especially in your ankle. Moxifloxacin can also have serious effects on your nerves, and may cause permanent nerve damage. Stop taking this medicine and inform your doctor if you have signs of tendon rupture-sudden pain, swelling, bruising, tenderness, stiffness, movement problems, or a snapping or popping sound in any of your joints (rest the joint until you receive medical care or instructions) or nerve symptoms-numbness, tingling, burning pain, or being more sensitive to temperature, light touch, or the sense of your body position. Common moxifloxacin side effects may include headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats muscle weakness or trouble breathing diarrhoea that is watery or bloody the first sign of any skin rash, no matter how mild sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, easy bruising or bleeding, pale or yellowed skin.

DRUG INTERACTION:

• Moxifloxacin+abarelix- Using moxifloxacin together with abarelix can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect. You may be more susceptible if you have a heart condition called congenital long QT syndrome, other cardiac diseases, conduction abnormalities, or electrolyte disturbances.
• Moxifloxacin+bosutinib- Using moxifloxacin together with bosutinib can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect. You may be more susceptible if you have a heart condition called congenital long QT syndrome, other cardiac diseases, conduction abnormalities, or electrolyte disturbances.
• Moxifloxacin+clomipramine- Using moxifloxacin together with clomipramine can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect. You may be more susceptible if you have a heart condition called congenital long QT syndrome, other cardiac diseases, conduction abnormalities, or electrolyte disturbances.
• Moxifloxacin+dolasetron- Using moxifloxacin together with dolasetron can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect. You may be more susceptible if you have a heart condition called congenital long QT syndrome, other cardiac diseases, conduction abnormalities, or electrolyte disturbances.

MECHANISM OF ACTION:

Moxifloxacin belongs to a group of antibiotics called fluoroquinolones. It kills a wide range of infection causing bacteria both gram positive and gram negative (broad spectrum). It acts by inhibiting enzymes (DNA gyrase and topoisomerase IV) involved in DNA processes that are essential for bacterial growth and survival thereby killing the bacteria.