Details

Aclarubicin is an anthracycline agent, prescribed for acute non-lymphocytic leukaemia. It has a selective inhibitory effect on the synthesis of RNA in the cells. Aclarubicin comes as a solution for injection to be administered by a doctor into the vein. Necessary precautions should be taken in patients with history of liver or kidney impairment, radiation-induced heart attack, and use of radiotherapy, during pregnancy and breastfeeding. Monitor complete blood counts, liver function, uric acid level in blood regularly while taking Aclarubicin.

Typical Uses

Aclarubicin is used mainly in combination with other drugs to treat a variety of cancers such as acute non-lymphoblastic leukaemia, ovarian cancer, breast cancer, thyroid cancer, stomach cancer, lymphoma, and small cell lung cancer.

Side Effects

Aclarubicin may lead to heart damage and bone marrow suppression, nausea, vomiting, irritant to tissue, hair loss, hepatic dysfunction, blood in urine, sore mouth, diarrhoea, and gastrointestinal tract inflammation.

Drug Interactions

Presently, there are no interactions for Aclarubicin.

Mechanism of action

Aclarubicin is an anti-cancer drug that belongs to a class of medicines called as cytotoxic anthracycline antibiotics. It works by stopping or slowing down the growth of cancerous cells by inhibiting the enzyme topoisomerase II needed for cell division in the body.

Pregnancy Category : D