Details of Topiramate Salt (Generic Drug)

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Details

Topiramate is a seizure medicine, also called an anticonvulsant. Topiramate is used to treat seizures in adults and children who are at least 2 years old. The Topamax brand of this medicine is also used to prevent migraine headaches in adults and teenagers who are at least 12 years old. Topamax will only prevent migraine headaches or reduce the number of attacks. It will not treat a headache that has already begun. To make sure topiramate is safe for you, tell your doctor if you have glaucoma or other eye problems diabetes, or a history of metabolic acidosis kidney disease, a history of kidney stones, or if you are on dialysis severe breathing problems a history of mood problems, depression, or suicidal thoughts or actions liver disease soft or brittle bones (osteoporosis, osteomalacia) a growth disorder if you take lithium or if you are sick with diarrhoea. Topiramate can increase the level of acid in your blood (metabolic acidosis). This can weaken your bones, cause kidney stones, or cause growth problems in children or harm to an unborn baby.


Typical Uses

Topiramate is used alone or with other medications to prevent and control seizures (epilepsy). This medication is also used to prevent migraine headaches and decrease how often you get them. Topiramate will not treat a migraine headache once it occurs. If you get a migraine headache, treat it as directed by your doctor (such as by taking pain medication, lying down in a dark room). Topiramate is known as an anticonvulsant or antiepileptic drug.


Side Effects

Common topiramate side effects may include vision problems, eye pain or redness, sudden vision loss (can be permanent if not treated quickly) confusion, slowed thinking, memory problems, trouble concentrating, problems with speech dehydration symptoms-decreased sweating, high fever, hot and dry skin signs of a kidney stone-severe pain in your side or lower back, painful or difficult urination signs of too much acid in your blood-irregular heartbeats, feeling tired, loss of appetite, trouble thinking, feeling short of breath or signs of too much ammonia in your blood-vomiting, unexplained weakness, feeling like you might pass out.


Drug Interactions

  • Topiramate+acetazolamide- Talk to your doctor before using acetazolamide together with topiramate. Both of these medications can cause metabolic acidosis, a condition associated with elevated levels of acid in the blood, and combining them may increase the risk as well as severity of the condition. Patients with metabolic acidosis may have no symptoms at all, or they may experience tiredness, loss of appetite, irregular heartbeat, trouble thinking clearly, and rapid breathing.
  • Topiramate+aripiprazole- Topiramate can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like aripiprazole. Heat stroke and hospitalization may occur in some people, especially in warm weather and during vigorous exercise. Children are particularly susceptible.
  • Topiramate+clozapine- Topiramate can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like clozapine. Heat stroke and hospitalization may occur in some people, especially in warm weather and during vigorous exercise. Children are particularly susceptible.
  • Topiramate+imipramine- Topiramate can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like imipramine. Heat stroke and hospitalization may occur in some people, especially in warm weather and during vigorous exercise. Children are particularly susceptible.


Mechanism of action

Topiramate belongs to a class of medicines known as anti-epileptic drugs. It decreases the abnormal and excessive electrical signals in the brain that cause seizures or fits.


Pregnancy Category : D


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