Details of Theophylline Salt (Generic Drug)



Theophylline is a bronchodilator. It works by relaxing muscles in the lungs and chest, making the lungs less sensitive to allergens and other causes of bronchospasm. Theophylline is used to treat symptoms such as wheezing or shortness of breath caused by asthma, bronchitis, emphysema, and other breathing problems. To make sure theophylline is safe for you, tell your doctor if you have a gastric or peptic ulcer epilepsy or other seizure disorder heart disease, high blood pressure, a heart rhythm disorder a high fever (102 degrees or higher) any chronic or recurrent illness fluid in your lungs a thyroid disorder liver disease (especially cirrhosis or hepatitis) kidney disease serious infection called sepsis enlarged prostate or urination problems a history of alcoholism or if you smoke or have recently quit smoking cigarettes or marijuana.

Typical Uses

Theophylline is used to treat and prevent wheezing and trouble breathing caused by ongoing lung disease (e.g., asthma, emphysema, chronic bronchitis). Theophylline belongs to a class of drugs known as xanthenes. It works in the airways by relaxing muscles, opening air passages to improve breathing, and decreasing the lungs' response to irritants.

Side Effects

Common theophylline side effects may include severe or continued vomiting rapid or uneven heartbeats seizure (convulsions) confusion, tremors or shaking nausea and vomiting, severe headache, rapid heart rate low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling) or high blood sugar (increased thirst, increased urination, hunger, dry mouth, fruity breath odour, drowsiness, dry skin, blurred vision, weight loss).

Drug Interactions

  • Theophylline+acebutolol- Ask your doctor before using acebutolol together with theophylline. Using these medications together can make acebutolol less effective and increase the effects of theophylline. Contact your doctor if you experience nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications.
  • Theophylline+tramadol- Tramadol may rarely cause seizures, and combining it with other medications that can also cause seizures such as theophylline may increase that risk. The interaction may be more likely if you are elderly, undergoing alcohol or drug withdrawal, have a history of seizures, or have a condition affecting the central nervous system such as a brain tumour or head trauma.
  • Theophylline+fluvoxamine- Fluvoxamine may significantly increase the blood levels of theophylline, which may lead to potentially serious and life-threatening side effects. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications.
  • Theophylline+metrizamide- Before you undergo any imaging procedure where metrizamide may be injected directly into the spine let your doctor know if you are currently being treated with theophylline. Injection of metrizamide into the spine can sometimes cause seizures, and the risk may be increased if you are also using other medications that can cause seizures such as theophylline.

Mechanism of action

Theophylline belongs to a class of drugs called xanthenes. It works in the airways by relaxing muscles, opening air passages to improve breathing, and decreasing the lungs response to irritants.

Pregnancy Category : C

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