Details of Fluorouracil Salt (Generic Drug)

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Details

Fluorouracil is a cancer medication that interferes with the growth and spread of cancer cells in the body. Fluorouracil is used to treat cancer of the colon, rectum, breast, stomach, or pancreas. To make sure fluorouracil is safe for you, tell your doctor if you have cancer that has spread to your bone marrow liver disease kidney disease or if you have ever had radiation treatment of your pelvic area. You should not receive this medicine if you are allergic to fluorouracil, or if you have bone marrow depression a serious infection or if you are malnourished or are not receiving proper nutrition. Do not use fluorouracil if you are pregnant.


Typical Uses

Fluorouracil is used to treat various types of cancer. It is a chemotherapy drug that is used alone or in combination with other medications to slow or stop cancer cell growth.


Side Effects

Common side effects of fluorouracil include signs of infection such as fever, chills, sore throat, flu symptoms white patches or sores inside your mouth or throat, or on your lips pale skin, easy bruising or bleeding (nosebleeds, bleeding gums, or any bleeding that will not stop) weakness or fainting bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds coughing up blood or vomit that looks like coffee grounds watery diarrhoea, ongoing or severe vomiting pain, redness, numbness, and peeling skin on your hands or feet numbness or tingling anywhere in your body, loss of muscle control or sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance.


Drug Interactions

• Fluorouracil+adalimumab- Using adalimumab together with fluorouracil may increase the risk of serious and potentially life-threatening infections. Talk to your doctor if you have any questions or concerns.

• Fluorouracil+anisindione- Using anisindione together with fluorouracil can cause you to bleed more easily. You may need a dose adjustment in addition to testing of your prothrombin time.

• Fluorouracil+deferiprone- Deferiprone can lower white blood cell count, and combining it with other medications that can also affect bone marrow function such as fluorouracil may increase the risk. You may be more likely to develop serious and potentially life-threatening infections as a result.

• Fluorouracil+clozapine- Using clozapine together with fluorouracil is not recommended. Clozapine can lower white blood cell count, and combining it with other medications that can also affect bone marrow function such as fluorouracil may increase the risk. You may be more likely to develop serious and potentially life-threatening infections as a result.

• Fluorouracil+dicumarol- Using dicumarol together with fluorouracil can cause you to bleed more easily. You may need a dose adjustment in addition to testing of your prothrombin time.

• Fluorouracil+golimumab- Using fluorouracil together with golimumab may increase the risk of serious and potentially life-threatening infections. Talk to your doctor if you have any questions or concerns.


Mechanism of action

Fluorouracil belongs to a class of medicines called pyrimidine analogues. It blocks the process which is essential for cell division as well as cell growth thus resulting in death of cancerous cells.


Pregnancy Category : D


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