Details of Erythromycin Salt (Generic Drug)

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Details

Erythromycin belongs in a group of drugs called macrolide antibiotics. Macrolide antibiotics slow the growth of, or sometimes kill, sensitive bacteria by reducing the production of important proteins needed by the bacteria to survive. Erythromycin is used to treat or prevent many different types of infections caused by bacteria. Some medicines can cause unwanted or dangerous effects when used with erythromycin. To make sure erythromycin is safe for you, tell your doctor if you have liver or kidney disease myasthenia gravis a heart rhythm disorder an electrolyte imbalance (such as low levels of potassium or magnesium in your blood) a history of Long QT syndrome or if you take medicine to treat a heart rhythm disorder.


Typical Uses

Erythromycin is used to treat a wide variety of bacterial infections. It may also be used to prevent certain bacterial infections. Erythromycin is known as a macrolide antibiotic. It works by stopping the growth of bacteria. This antibiotic treats or prevents only bacterial infections. It will not work for viral infections (such as common cold, flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness. Erythromycin may also be used to treat a certain type of stomach condition involving slowed digestion (gastroparesis).


Side Effects

Common side effects of erythromycin include diarrhoea that is watery or bloody headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats hearing problems (rare) liver problemsnausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-coloured stools, jaundice (yellowing of the skin or eyes) or severe skin reaction fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling. Older adults may be more likely to have serious side effects from erythromycin, including hearing loss, or a life-threatening fast heart rate.


Drug Interactions

• Erythromycin+anisindione- Using erythromycin together with anisindione may cause you to bleed more easily. You may need a dose adjustment based on your prothrombin time.

• Erythromycin+axitinib- Erythromycin may significantly increase the blood levels of axitinib. This may increase side effects such as high blood pressure, diarrhoea, nausea, vomiting, constipation, decreased appetite, weight loss, and rash, itching or peeling of skin on the hands and feet. You may also be more likely to experience less common but more severe side effects such as blood clots (depending on location, can lead to complications such as stroke, heart attack, breathing difficulties, and vision abnormalities) bleeding liver problems thyroid problems tearing (perforation) in the stomach or intestinal wall and a rare nervous system condition known as reversible posterior leukoencephalopathy syndrome (RPLS).

• Erythromycin+bedaquiline- Using bedaquiline together with erythromycin can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect. You may be more susceptible if you have a heart condition called congenital long QT syndrome, other cardiac diseases, conduction abnormalities, or electrolyte disturbances.

• Erythromycin+cilostazol- Erythromycin may significantly increase the blood levels of


Mechanism of action

Erythromycin belongs to class of medications called macrolide antibiotics. Erythromycin inhibits bacterial protein synthesis, thereby stopping the bacterial growth or sometimes killing sensitive bacteria.


Pregnancy Category : B


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