Details of Celecoxib Salt (Generic Drug)



Celecoxib is a non-steroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. Celecoxib is used to treat pain or inflammation caused by many conditions such as arthritis, ankylosing spondylitis, and menstrual pain. Celecoxib is used to treat juvenile rheumatoid arthritis in children who are at least 2 years old. It is also used in the treatment of hereditary polyps in the colon. Celecoxib can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Do not use this medicine just before or after heart bypass surgery. To make sure celecoxib is safe for you, tell your doctor if you have heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke a history of heart attack, stroke, or blood clot a history of stomach ulcers or bleeding asthma liver or kidney disease or fluid retention. Taking celecoxib during the last 3 months of pregnancy may harm the unborn baby.

Typical Uses

Celecoxib is a non-steroidal anti-inflammatory drug (NSAID), specifically a COX-2 inhibitor, which relieves pain and swelling (inflammation). It is used to treat arthritis, acute pain, and menstrual pain and discomfort. The pain and swelling relief provided by this medication helps you perform more of your normal daily activities. If you are treating a chronic condition such as arthritis, ask your doctor about non-drug treatments or using other medications to treat your pain. Celecoxib works by blocking the enzyme in your body that makes prostaglandins. Decreasing prostaglandins helps to reduce pain and swelling. This medication may also be used to treat gout attacks.

Side Effects

Stop using celecoxib and contact your medical professional immediately if you have the first sign of any skin rash, no matter how mild shortness of breath (even with mild exertion) swelling or rapid weight gain signs of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds liver problems - nausea, upper stomach pain, itching, tired feeling, flu-like symptoms, loss of appetite, dark urine, clay-coloured stools, jaundice (yellowing of the skin or eyes) kidney problems - little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath low red blood cells (anaemia) - pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating or severe skin reaction - fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Drug Interactions

• Celecoxib+adefovir- Talk to your doctor before using adefovir together with celecoxib. Adefovir may cause kidney problems, and combining it with other medications that can also affect the kidney such as celecoxib may increase that risk. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications.

• Celecoxib+cidofovir- Using cidofovir together with celecoxib is not recommended. Cidofovir may cause kidney damage, and combining it with other medications that can also affect the kidney such as celecoxib may increase that risk. If you have been receiving celecoxib, you may need to wait at least seven days after your last dose before you can start treatment with cidofovir.

• Celecoxib+deferasirox- Talk to your doctor before using deferasirox together with celecoxib. Combining these medications may increase your risk of developing gastrointestinal ulcers and bleeding. If you use celecoxib frequently or regularly (for example, to treat arthritis or chronic pain), you may also have an increased risk of kidney problems during treatment with deferasirox. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications.

• Celecoxib+ketorolac- Using celecoxib and ketorolac is not recommended. Using celecoxib together with ketorolac can cause nausea, vomiting, stomach pain, drowsiness, black or bloody stools, coughing up blood, urinating less than usual, and shallow breathing.

Mechanism of action

Celecoxib is a pain killer belongs to a category of drugs called as COX-2 inhibitors. It inhibits the formation of chemicals called prostaglandins, which is responsible for causing pain and inflammation, thereby reducing the pain and swelling symptoms.

Pregnancy Category : C

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