Details of Naproxen Salt (Generic Drug)

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Details

Naproxen is a non-steroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. Naproxen is used to treat pain or inflammation caused by conditions such as arthritis, ankylosing spondylitis, tendinitis, bursitis, gout, or menstrual cramps. The delayed-release or extended-release tablets are slower-acting forms of naproxen that are used only for treating chronic conditions such as arthritis or ankylosing spondylitis. These forms will not work fast enough to treat acute pain. Naproxen can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Naproxen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults. Ask a doctor if it is safe for you to use this medicine if you have heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke a history of heart attack, stroke, or blood clot a history of stomach ulcers or bleeding asthma liver or kidney disease or fluid retention. Naproxen should not be used in the last trimester of pregnancy.


Typical Uses

Naproxen is used to relieve pain from various conditions such as headaches, muscle aches, tendonitis, dental pain, and menstrual cramps. It also reduces pain, swelling, and joint stiffness caused by arthritis, bursitis, and gout attacks. This medication is known as a non-steroidal anti-inflammatory drug (NSAID). It works by blocking your body's production of certain natural substances that cause inflammation.


Side Effects

Get immediate medical assistance if you experience chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech or feeling short of breath. Common naproxen side effects may include shortness of breath (even with mild exertion) swelling or rapid weight gain the first sign of any skin rash, no matter how mild signs of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds liver problems - nausea, upper stomach pain, itching, tired feeling, flu-like symptoms, loss of appetite, dark urine, clay-coloured stools, jaundice (yellowing of the skin or eyes) kidney problems - little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath low red blood cells (anaemia) - pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating or severe skin reaction - fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.


Drug Interactions

  • Naproxen+adefovir- Talk to your doctor before using adefovir together with naproxen. Adefovir may cause kidney problems, and combining it with other medications that can also affect the kidney such as naproxen may increase that risk. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications.
  • Naproxen+desirudin- Using desirudin together with naproxen may increase the risk of bleeding, including severe and sometimes fatal haemorrhage. Talk to your doctor if you have any questions or concerns.
  • Naproxen+leflunomide- Leflunomide may cause liver damage and taking it with other medications that can also affect the liver such as naproxen may increase that risk. You should avoid or limit the use of alcohol while being treated with these medications.
  • Naproxen+ponatinib- Using ponatinib together with naproxen may increase the risk of bleeding. In clinical studies, treatment with ponatinib alone has been associated with severe and sometimes fatal haemorrhage. Talk to your doctor if you have any questions or concerns.
  • Naproxen+tinzaparin- Talk to your doctor before using tinzaparin together with naproxen. Combining these medications can increase the risk of bleeding complications. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications.


Mechanism of action

Naproxen belongs to a class of medications called non-steroidal anti-inflammatory drugs (NSAIDs) which works by blocking the effect of enzyme called cyclooxygenase resulting in decreased production of prostaglandins (a chemical associated with pain) thereby causing ease of pain and inflammation.


Pregnancy Category : C


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