Details of Levothyroxine Salt (Generic Drug)

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Details

Levothyroxine is a replacement for a hormone normally produced by your thyroid gland to regulate the body's energy and metabolism. Levothyroxine is given when the thyroid does not produce enough of this hormone on its own. Levothyroxine treats hypothyroidism (low thyroid hormone). It is also used to treat or prevent goitre (enlarged thyroid gland), which can be caused by hormone imbalances, radiation treatment, surgery, or cancer. Since thyroid hormone occurs naturally in the body, almost anyone can take levothyroxine. To make sure levothyroxine is safe for you, tell your doctor if you have a thyroid disorder called thyrotoxicosis heart disease, coronary artery disease, or a history of blood clots diabetes (insulin or oral diabetes medication doses may need to be changed when you start taking levothyroxine) anaemia (lack of red blood cells) osteoporosis, or low bone mineral density problems with your pituitary gland any food or drug allergies an untreated or uncontrolled adrenal gland disorder or if you have recently had a heart attack, or are having any symptoms of a heart attack (chest pain or heavy feeling, pain spreading to the jaw or shoulder, nausea, sweating, general ill feeling).


Typical Uses

Levothyroxine is used to treat an underactive thyroid (hypothyroidism). It replaces or provides more thyroid hormone, which is normally produced by the thyroid gland. Low thyroid hormone levels can occur naturally or when the thyroid gland is injured by radiation/medications or removed by surgery. Having enough thyroid hormone is important for maintaining normal mental and physical activity. In children, having enough thyroid hormone is important for normal mental and physical development. This medication is also used to treat other types of thyroid disorders (such as certain types of goitres, thyroid cancer). Levothyroxine should not be used to treat infertility unless it is caused by low thyroid hormone levels.


Side Effects

Common levothyroxine side effects may include fast or irregular heart rate fever, hot flashes, sweating sleep problems (insomnia) changes in your menstrual periods or vomiting, diarrhoea, appetite changes, weight changes.


Drug Interactions

  • Levothyroxine+acarbose- Levothyroxine may interfere with blood glucose control and reduce the effectiveness of acarbose and other diabetic medications. Monitor your blood sugar levels closely. You may need a dose adjustment of your diabetic medications during and after treatment with levothyroxine.
  • Levothyroxine+alogliptin- Levothyroxine may interfere with blood glucose control and reduce the effectiveness of alogliptin and other diabetic medications. Monitor your blood sugar levels closely. You may need a dose adjustment of your diabetic medications during and after treatment with levothyroxine.
  • Levothyroxine+amiodarone- Amiodarone may reduce the effects of levothyroxine. Contact your doctor if your symptoms worsen or your condition changes. Your doctor may be able to adjust the dose of levothyroxine or prescribe alternatives that do not interact.
  • Levothyroxine+butalbital- Using butalbital together with levothyroxine can decrease the effects of butalbital. This can cause fatigue, weight gain, constipation, and low blood pressure. Talk with your doctor before using these medications together, and report any side effects promptly.
  • Levothyroxine+ciprofloxacin- Using ciprofloxacin together with levothyroxine can decrease the effects of levothyroxine. You should separate administration of ciprofloxacin and levothyroxine by several hours to minimize any effect this could have. Talk with your doctor before using ciprofloxacin while you are using levothyroxine.
  • Levothyroxine+danazol- Before using levothyroxine, tell your doctor if you also use danazol. You may need a dose adju


Mechanism of action

Levothyroxine is in a class of medications called hormones. It works by replacing thyroid hormone that is normally produced by the body.


Pregnancy Category : A


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