Details of Glycopyrrolate Salt (Generic Drug)

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Details

Glycopyrrolate reduces the secretions of certain organs in the body. Glycopyrrolate helps to control conditions such as peptic ulcers that involve excessive stomach acid production. Glycopyrrolate is also used to reduce drooling in children ages 3 to 16 who have certain medical conditions, such as cerebral palsy. Before you take glycopyrrolate, tell your doctor if you have kidney disease, heart disease, a heart rhythm disorder, a stomach disorder, a colostomy or ileostomy, a thyroid disorder, high blood pressure, vision problems, or numbness and tingling. You should not use glycopyrrolate if you are allergic to it, or if you have bladder obstruction or other urination problems, a bowel obstruction called paralytic ileus, a blockage in your stomach or intestines, severe constipation, severe ulcerative colitis or toxic megacolon, glaucoma, myasthenia gravis, or if you also take potassium chloride.


Typical Uses

Glycopyrrolate is used with other drugs to treat a certain type of stomach/intestinal ulcer (peptic ulcer). This medication may help relieve stomach/abdominal pain. However, it has not been shown to be effective in healing these ulcers, preventing them from returning, or preventing other problems caused by ulcers. Glycopyrrolate works by decreasing the amount of acid in the stomach. It also slows the natural movements of the gut and relaxes the muscles in the stomach/intestines. Glycopyrrolate belongs to a class of drugs known as anticholinergics.


Side Effects

Common side effects of glycopyrrolate include severe constipation, severe stomach pain and bloating diarrhoea (especially if you have a colostomy or ileostomy) feeling like you might pass out feeling very thirsty or hot, being unable to urinate, heavy sweating, weak pulse, or hot and dry skin or dry diapers, fussiness, or excessive crying in a child taking glycopyrrolate.


Drug Interactions

  • Glycopyrrolate+topiramate- Topiramate can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like glycopyrrolate. Heat stroke and hospitalization may occur in some people, especially in warm weather and during vigorous exercise. Children are particularly susceptible. Talk to your doctor if you have any questions or concerns.
  • Glycopyrrolate+potassium chloride- Talk to your doctor before using potassium oral tablets or capsules together with glycopyrrolate. Depending on the dose of glycopyrrolate and your overall physical health, combining these medications may increase the irritant effects of potassium on your stomach and upper intestine. This can rarely result in ulcers, bleeding, and other gastrointestinal injury.
  • Glycopyrrolate+zonisamide- Zonisamide can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like glycopyrrolate. Heat stroke and hospitalization may occur in some people, especially in warm weather and during vigorous exercise. Children are particularly susceptible. Talk to your doctor if you have any questions or concerns.


Mechanism of action

Glycopyrrolate belongs to a class of medications called anticholinergics. It decreases the secretions in the mouth, throat, airways and stomach acid.


Pregnancy Category : B


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