What is Angioedema?
- Angioedema, also known as Quincke's edema is described as the rapid swelling of dermis (skin), mucus, and submucosal tissues. Angioedema usually affects the deeper part of the skin, commonly around the face and lips. Angioedema is also defined as an acute mast of cell-mediated reaction caused by exposure to drug, venom, pollen, or animal allergens. The swelling (localized) is due to vascular and intravascular fluid leakages. The skin around the eyes, lips, genitals, hands, and feet swell and develops into red, itchy patches called hives or urticaria on the skin surface.
- Angioedema is a related type of swelling that affects deeper layers in your skin, often around your face and lips. In most cases, hives and angioedema are harmless and don't leave any lasting marks, even without treatment.
- Angioedema is classified into two main types: Acquired Angioedema (AAE) and Hereditary Angioedema (HAE). Acquired Angioedema (AAE) is usually caused by allergy, and can be a side-effect of certain medicines like ACE inhibitors. Hereditary Angioedema (HAE) is caused by genetic mutations inherited from the family. These are distinguished by underlying genetic abnormalities.
- When angioedema is passed from a parent to a child through genetic transmission, the condition is known as hereditary angioedema. Hereditary angioedema has different causes, symptoms, treatments, and complications than acquired angioedema.
- Angioedema generally isn't a serious medical condition and doesn't leave any lasting marks. Angioedema usually goes away on its own, even without treatment.
What are the symptoms of angioedema?
The main symptom of angioedema is swelling which develops below the skin surface. The swelling occurs on face around eyes, lips, mouth, hands, and feet, and in certain cases it is genital. The swelling then develops into red, itchy patches called urticaria (hives). The rashes subside in a few days, but skin may look painful. Common symptoms of angioedema are:
What is the cost for the treatment of angioedema in India?
Which specialty of doctor is to be consulted for the treatment of angioedema in India?
Which hospital is to be preferred for the treatment of angioedema in India?
1. What are the causes of angioedema?
- Angioedema is typically the result of an allergic reaction. When you have an allergic reaction, your body produces histamine, which makes your blood vessels swell. Some of the most probable causes of angioedema include:
- Vigorous exercise
- Stress and anxiety
- Minor infections
2. Who is at risk for angioedema?
- Individual have high risk of Angioedema if they have:
- Previous history
- Allergic reactions
- Disorder associated with angioedema such as lupus, lymphoma, or thyroid disease
- Family history or hereditary angioedema
3. What are the possible ways to prevent angioedema?
- The best way to prevent angioedema is to avoid known and suspected allergens. You should also try not to irritate areas on the body that have been previously affected. Taking these preventive measures can help lower your risk of having another episode in the future.
4. How is angioedema diagnosed?
- At Medanta in India, doctor may examine the affected area and will take details of the symptoms and past medical history. The details will include probable symptoms which occur, or worsen later. Few tests which may be conducted to pinpoint the type of angioedema are:
- Routine blood test like CBC
- Electrolytes enzyme test
- Renal function test
- Allergy Test
- Skin prick test
- Blood Test
5. How is angioedema treated?
- At Medanta in India, the treatment of angioedema helps in getting relief from intense itching, and discomfort that persists.
- Anti-itching Drugs
Standard treatment- antihistamines are prescribed to reduce itching, swelling, and other symptoms.
Doctors may prescribe oral corticosteroid drug (prednisone) to reduce swelling, redness, and itching.
- Immunity Suppressing drugs
When anti-inflammatory and anti-itching drugs prove ineffective, doctors prescribe medicines capable of calming overactive immune system.
- Blood protein controllers
Medicines that regulate levels of blood proteins are prescribed to people who suffer from hereditary angioedema.