- Posted on- Oct 23, 2015
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Myasthenia Gravis is a neuromuscular disorder primarily characterized by muscle weakness and muscle fatigue. Although the disorder usually becomes apparent during adulthood, symptom onset may occur at any age. The condition may be restricted to certain muscle groups, particularly those of the eyes (ocular myasthenia gravis), or may become more generalized (generalized myasthenia gravis), involving multiple muscle groups. Most individuals with myasthenia gravis develop weakness and drooping of the eyelids (ptosis) weakness of eye muscles, resulting in double vision (diplopia) and excessive muscle fatigue following activity.
What are the causes of Myasthenia Gravis?
Myasthenia Gravis is a neuromuscular disorder that is usually caused by an autoimmune problem. Autoimmune disorders occur when the immune system mistakenly attacks healthy tissue. In this condition, antibodies (proteins which normally attack foreign, harmful substances in the body) attack the neurotransmitter substance called acetylcholine, which is a crucial substance for nerve cell and muscle communication. This results in the muscle weakness that characterizes the condition. The exact cause of this autoimmune reaction is unclear to the doctors.
Who is at risk?
Myasthenia Gravis is not inherited, and it is not contagious. It is not clear why people develop the disorder, although some researchers believe it could be from a genetic problem. For women, the disorder usually starts in their 20s and 30s for men, usually after age 50.