- Posted on- Aug 03, 2015
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Castleman Disease is a rare disease in which the body's disease-fighting network (lymphatic system) contains more than required cells (overgrowth of cells). It is also known as giant lymph node hyperplasia and angiofollicular lymph node hyperplasia. Castleman disease can occur in a unicentric (localized) or multicentric (widespread) form.
Multicentric Castleman disease can be life-threatening because sometimes it is linked with HIV infection. It is also associated with other cell-proliferation disorders, including cancer of the lymphatic system (lymphoma), Kaposi's sarcoma and POEMS syndrome.