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Test Details
Test Code:PL0468
Test Name:Factor XII Assay
Test Details & Preparation
The factor XII assay is a blood test to measure the activity of factor XII - one of the substances involved in blood clotting. It is also known as Hageman factor assay.

Blood is typically drawn from a vein, usually from the inside of the elbow or the back of the hand. The area is cleaned with germ-killing medicine (antiseptic). The health care provider wraps an elastic band around the upper arm to apply pressure to the area and make the vein swell with blood.

Next, the doctor gently inserts a needle into the vein. The blood collects into an airtight vial or tube attached to the needle. The elastic band is removed from your arm. Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.



In infants or young children, a sharp tool called a lancet may be used to puncture the skin and make it bleed. The blood collects into a small glass tube called a pipette, or onto a slide or test strip. A bandage may be placed over the area if there is any bleeding.

There is no special preparation needed for a factor XII assay test.

A normal value is 50 - 200% of the laboratory control or reference value. Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results. Decreased factor XII activity may indicate congenital deficiency of factor XII or liver disease.

People with factor XII deficiency usually do not have excess bleeding. Factor XII does not appear to be needed for clots to form during the normal process of stopping bleeding.
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