• Test Code - PL0459
  • Test Name - Estrogen and Progesterone Receptor Status
  • Views - 776 Views
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Test Details & Preparation

  • Oestrogen and Progesterone Receptor Status test is done when the hormone receptor test determines if a breast cancer tumour is positive for oestrogen and progesterone receptors, helping to guide treatment and determine prognosis.

  • Oestrogen and Progesterone Receptor Status test is performed when you have been diagnosed with invasive breast cancer or when your cancer has recurred.

  • A sample of breast cancer tissue obtained during a biopsy or a tumour removed surgically during a lumpectomy or mastectomy.

  • Your doctor may have you discontinue taking hormones for a time period before your sample is collected.

  • In general, if a person's cancer is ER-positive and PR-positive, the individual will have a better than average prognosis, and their cancer is likely to respond to endocrine therapy such as tamoxifen.

  • If a person's cancer is ER-negative but PR-positive, or ER-positive but PR-negative, then she may still benefit from endocrine therapy but may have a diminished response.

  • If the cancer is both ER-negative and PR-negative, then the person is not likely to benefit from endocrine therapy.

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